Statement from FDA Commissioner Scott Gottlieb, M.D., on a new qualified health claim advising that early introduction of peanuts to certain high-risk infants may reduce risk of peanut allergy - FDA Press Releases

Statement from FDA Commissioner Scott Gottlieb, M.D., on a new qualified health claim advising that early introduction of peanuts to certain high-risk infants may reduce risk of peanut allergy

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Genentech Issues Voluntary Nationwide Recall of Three Lots of Activase® (Alteplase)-100 mg Due to Lack of Sterility Assurance of the Sterile Water for Injection - FDA Safety Alerts & Drug Recalls

Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), is voluntarily recalling three lots of Activase® (alteplase) 100mg vials, that were co-packaged with Sterile Water for Injection, to the hospital level. The vials of Sterile Water for Injection, manufactured by Hospira Inc., a Pfizer company, and packaged with Activase 100 mg, may be cracked or chipped at the neck of the vial and leaking.

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The Age-Friendly Health System Imperative - American Geriatric Society

The unprecedented changes happening in the American healthcare system have many on high alert as they try to anticipate legislative actions. Significant efforts to move from volume to value, along with changing incentives and alternative payment models, will affect practice and the health system budget. In tandem, growth in the population aged 65 and older is celebratory and daunting. The John A. Hartford Foundation is partnering with the Institute for Healthcare Improvement to envision an age-friendly health system of the future. Our current prototyping for new ways of addressing the complex and interrelated needs of older adults provides great promise for a more-effective, patient-directed, safer healthcare system. Proactive models that address potential health needs, prevent avoidable harms, and improve care of people with complex needs are essential. The robust engagement of family caregivers, along with an appreciation for the value of excellent communication across care settings, is at the heart of our work. Five early-adopter health systems are testing the prototypes with continuous improvement efforts that will streamline and enhance our approach to geriatric care.

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Surveillance for highly pathogenic influenza A viruses in California during 2014–2015 provides insights into viral evolutionary pathways and the spatiotemporal extent of viruses in the Pacific Americas Flyway

Surveillance for highly pathogenic influenza A viruses in California during 2014–2015 provides insights into viral evolutionary pathways and the spatiotemporal extent of viruses in the Pacific Americas Flyway

Emerging Microbes & Infections 6, e80 (September 2017). doi:10.1038/emi.2017.66

Authors: Andrew M Ramey, Nichola J Hill, Troy Cline, Magdalena Plancarte, Susan De La Cruz, Michael L Casazza, Joshua T Ackerman, Joseph P Fleskes, T Winston Vickers, Andrew B Reeves, Frances Gulland, Christine Fontaine, Diann J Prosser, Jonathan A Runstadler & Walter M Boyce

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Disease reservoirs: from conceptual frameworks to applicable criteria

Disease reservoirs: from conceptual frameworks to applicable criteria

Emerging Microbes & Infections 6, e79 (September 2017). doi:10.1038/emi.2017.65

Authors: Luisa K Hallmaier-Wacker, Vincent J Munster & Sascha Knauf

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To announce or not to announce: What is known about the 2016–2017 influenza season in Hong Kong?

To announce or not to announce: What is known about the 2016–2017 influenza season in Hong Kong?

Emerging Microbes & Infections 6, e78 (September 2017). doi:10.1038/emi.2017.76

Authors: Pak-Hin Hinson Cheung, Chi-Ping Chan & Dong-Yan Jin

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Cancer Screening of Older Adults in Israel According to Life Expectancy: Cross Sectional Study - American Geriatric Society

Objectives

To examine over-screening of older Israelis for colon and breast cancer.

Design

Cross sectional.

Setting

Clalit Health Services (CHS), Israel's largest health maintenance organization (HMO), provides care for more than half of the country's population and operates a national age-based programs for cancer screening.

Participants

All community-dwelling members aged 65 to 79 in 2014 (N = 370,876).

Measurements

We used CHS data warehouse to evaluate cancer screening during 2014. Life expectancy (LE) was estimated using the validated Schonberg index.

Results

Almost one-quarter (23.1%; 15.6% of adults aged 65–74, 42.7% of adults aged 75–79) of the study population had an estimated LE of less than 10 years. Annual fecal occult blood test and biannual mammography rates among adults aged 65 to 74 with a LE of 10 years or longer were 37.1% and 70.0%, respectively. Rates dropped after age 75 (4.0%, 19.5%) and to a lesser extent with a LE of less than 10 years (31.6%, 56.4%). Prostate-specific antigen testing is not part of the national screening program, and the proportion of people tested (42.6%), did not vary similarly with age of 75 and older (43.2%) or LE of less than 10 years (38.1%).

Conclusion

The cancer screening inclusion criteria of the national referral system have a strong effect on receipt of screening; LE considerations are less influential. Some method of estimating LE could be incorporated into algorithms to improve individualized cancer screening to reduce over- and underscreening of older adults.

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