Tuesday, March 3, 2020

FDA Informs Patients, Providers and Manufacturers About Potential Cybersecurity Vulnerabilities in Certain Medical Devices with Bluetooth Low Energy - FDA Press Releases

FDA warns patients, providers and manufacturers about potential SweynTooth cybersecurity vulnerabilities in Bluetooth Low Energy wireless communication.

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Monday, March 2, 2020

Coronavirus (COVID-19) Update: FDA and CDC take action to increase access to respirators, including N95s, for health care personnel - FDA Press Releases

Coronavirus Update: FDA and CDC take action to increase access to respirators, including N95s, for health care personnel

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FDA Approves New Therapy for Patients with Previously Treated Multiple Myeloma - FDA Press Releases

FDA approved Sarclisa (isatuximab-irfc), in combination with pomalidomide and dexamethasone, for the treatment of adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor

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Antifungal peptides produced by actinomycetes and their biological activities against plant diseases - Journal of Antibiotics

The Journal of Antibiotics, Published online: 02 March 2020; doi:10.1038/s41429-020-0287-4

Antifungal peptides produced by actinomycetes and their biological activities against plant diseases

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Saturday, February 29, 2020

Wish to Die in Older Patients: Development and Validation of Two Assessment Instruments - American Geriatric Society

OBJECTIVES

The wish to die may be different in geriatric patients than in younger terminally ill patients. This study aimed to develop and validate instruments for assessing the wish to die in geriatric patients.

DESIGN

Cross‐sectional study.

SETTING

Geriatric rehabilitation unit of a university hospital.

PARTICIPANTS

Patients (N = 101) aged 65 years or older with a Mini‐Mental State Examination score of 20 or higher, admitted consecutively over a 5‐month period.

MEASUREMENTS

The Schedule of Attitudes Toward Hastened Death (SAHD) was adapted to the older population (SAHD‐Senior). A second tool was developed based on qualitative literature, the Categories of Attitudes Toward Death Occurrence (CADO). After cognitive pretesting, these instruments were validated in a sample of patients admitted to a geriatric rehabilitation unit.

RESULTS

The SAHD‐Senior showed good psychometric properties and a unifactorial structure. In the studied sample, 12.9% had a SAHD‐Senior score of 10 or higher, suggesting a significant wish to die. Associations were observed between high levels of the SAHD‐Senior and advanced age, high levels of depressive symptoms, lower quality of life, and lower cognitive function. The CADO allowed for passive death wishes to be distinguished from wishes to actively hasten death. According to the CADO, 14.9% of the sample had a wish to die. The two instruments showed a concordance rate of 90.1%.

CONCLUSION

The wish to die in older patients admitted to rehabilitation can be validly assessed with two novel instruments. The considerable proportion with a wish to die warrants investigation into concept, determinants, and management of the wish to die.



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Reply to Comment on: End‐of‐Life Decision Making and Treatment for Patients With Professional Guardians - American Geriatric Society

Journal of the American Geriatrics Society, EarlyView.

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Comment on: End‐of‐Life Decision Making and Treatment for Patients With Professional Guardians - American Geriatric Society

Journal of the American Geriatrics Society, EarlyView.

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