Objectives
To determine the role of physical activity as a possible survival determinant in the oldest adults.
Design
Prospective, longitudinal, population-based cohort.
Setting
The Pianoro Study of community-dwelling older adults in three towns in northern Italy.
Participants
Noninstitutionalized individuals aged 85 and older (n = 500; mean age 89.6 ± 3.1, 65% female).
Measurements
Participants provided information on marital status, educational level, previous work activity, cardiovascular risk factors, previous cardiovascular events, self-rated health, joint pain, and functional status. Physical activity was quantified using the Physical Activity Scale for the Elderly. Seven-year mortality was known for all subjects.
Results
During the 7 years of follow-up, 365 subjects died. According to Cox proportional hazards regression, the following factors were found to be independently associated with mortality: PASE score (hazard ratio (HR) = 0.987, 95% confidence interval (CI) = 0.981–0.993, P < .001), male sex (HR = 1.642, 95% CI = 1.411–2.068, P < .001), age in years (HR = 1.077, 95% CI = 1.040–1.116, P < .001), previous stroke (HR = 1.908, 95% CI = 1.362–2.673, P < .001), poor self care (HR = 1.662, 95% CI = 1.231–2.246, P < .001), neck pain (HR = 0.649, 95% CI = 0.497–0.849, P = .002), self rated health (HR = 0.991, 95% CI = 0.985–0.997, P = .002).
Conclusion
In the oldest adults, accurate quantification of physical activity may provide important prognostic information. The predictive value of cardiovascular risk factors, except age, male sex, and prior stroke, was confirmed to be negligible. An unexpected inverse association between neck pain and mortality may require further investigation.
from Journal of the American Geriatrics Society http://ift.tt/2gFPAGp
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