Objectives
To examine the association between midlife cardiovascular health and physical performance 25 years later.
Design
Cohort study (Atherosclerosis Risk in Communities Study); multinomial logistic and logistic regression adjusted for demographic characteristics and clinical measures.
Setting
Four U.S. communities: Forsyth County, North Carolina; Washington County, Maryland; Minneapolis, Minnesota; and Jackson, Mississippi.
Participants: Individuals aged 54.2 ± 5.8 at baseline (N = 15,744; 55% female, 27% black).
Measurements
Cardiovascular health was measured at baseline using the American Heart Association's Life's Simple 7 (LS7) score (0–14) and LS7 component categories (poor, intermediate, ideal) for each risk factor. The Short Physical Performance Battery (SPPB) was used to quantify physical function as ordinal (0–12) and categorical (low (0–6), fair (7–9), good (10–12) outcomes.
Results
Mean baseline LS7 score was 7.9 ± 2.4; 6,144 (39%) individuals returned 25 years later for the fifth ARIC examination, at which point the SPPB was administered. Of 5,916 individuals who completed the SPPB, 3,288 (50%) had good physical performance. Each 1-unit increase in LS7 score was associated with a 17% higher SPPB score (rate ratio (RR) = 1.17, 95% confidence interval (CI) = 1.15–1.19) and a 29% greater chance of having a late-life SPPB score of 10 or greater compared to SPPB score of less than 10 (RR = 1.29, 95% CI = 1.25–1.34). Ideal baseline glucose (RR = 2.53, 95% CI = 2.24–2.87), smoking (RR = 1.97, 95% CI = 1.81–2.15), blood pressure (RR = 1.70, 95% CI = 1.54–1.88), body mass index (RR = 1.51, 95% CI = 1.37–1.66), and physical activity (RR = 1.31, 95% CI = 1.20–1.43) had the strongest associations with late-life SPPB score, adjusting for other LS7 components.
Conclusion
Better cardiovascular health during midlife may lead better physical functioning in older age.
from Journal of the American Geriatrics Society http://ift.tt/2jUgvf2
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